The roles of anti-inflammation and analgesia of Qinghouxiaoyan granules
10.3969/j.issn.1006-5725.2015.23.008
- VernacularTitle:清喉消炎颗粒抗炎、镇痛作用研究
- Author:
Leshan HUANG
;
Hanhui HUANG
;
Yuehong WU
;
Pengke YAN
- Publication Type:Journal Article
- Keywords:
Qinghouxiaoyan granules;
Anti-inflammation;
Analgesia
- From:
The Journal of Practical Medicine
2015;31(23):3843-3846
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the anti-inflammatory and analgesic efects of Qinghouxiaoyan granules. Methods The rats were divided into blank group , Qinghouxiaoyan granules of high , medium , or low dose group, and aspirin group. Xylol-induced auricle swelling, carrageenan-induced paw swelling, Hac-induced blood capillary lealkage , and cotton pellet-induced graunloma were performed to assess the inflammatory effect; heat-plate test and Hac induced-twisting method were used to observe the analgesic efect. Results Qinghouxiaoyan granules played significant inhibitory action on xylene-induced inflammation , carrageenan-induced inflammation , and cotton-ball-induce granulation edema in different degrees; and decreased HAc-induced abdominal capillary permeability. The granules also showed significant analgesic effects on pain induced by heat and chemical stimu-lation in rats. Conclusion Qinghouxiaoyan granules has significant anti-inflammatory and analgesic effects.
