Incidence and risk factors of anemia in 400 patients with early breast cancer treated by chemotherapy

VernacularTitle:400例早期乳腺癌化疗过程中贫血发生率及相关因素
Author: Gengxi CAI ; Qing LIU ; Guangyu YAO ; Lujia CHEN ; Changsheng YE
Publication Type:Journal Article
Keywords: Breast cancer; Chemotherapy; Anemia; Incidence; Factors
From: The Journal of Practical Medicine 2015;31(23):3898-3900
CountryChina
Language:Chinese
Abstract: Objective To explore the incidence and predictive factors of anemia induced by chemothera-py in early breast cancer patients. Methods 400 early breast cancer patients treated by taxane-based regimens from 2009 to 2011 in our hospital were analyzed to obtain the incidence of anemia. Univariate analysis and multivariate logistic regression analysis were used to search for risk factors linked to the occurrence of anemia. Results Incidence of anemia was 72.2% in early breast cancer patients undergoing chemotherapy. The occur-rence of anemia was related to 5 risk factors: chemotherapy regiments, Hb at baseline < 135.0 g/L, age > 60 years old, BMI ≤ 25 kg/m2 and HBV antigen positive. Conclusion The anemia incidence during chemothera-py is high in early breast cancer patients. Such factors,as chemotherapy regiments, Hb at baseline, age, BMI and HBV antigen, should be taken into account in identifying high risk patients and prevent anemia.