Study on flow cytometry for detecting T lymphocytes in patients with dengue fever
10.3969/j.issn.1673-4130.2015.24.013
- VernacularTitle:流式细胞术检测登革热患者 T 淋巴细胞研究
- Author:
Yaling SHI
;
Rong ZHAO
;
Weilie CHEN
- Publication Type:Journal Article
- Keywords:
flow cytometry;
dengue fever;
immune status
- From:
International Journal of Laboratory Medicine
2015;(24):3541-3542
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigarte the immune status in the patients with dengue fever .Methods The flow cytometry was used to detect the T lymphocytes in the patients with dengue fever for analyzing their immune status .Results Compared with the reference range in the healthy individuals ,it was found that the T lymphocyte proportion in the patients with dengue fever was sig‐nificantly reduced compared with the healthy individuals .The percentages of CD3+CD4+ and CD3+CD8+ lymphocytes were (36 .54 ± 9 .78)% and (17 .7 ± 10 .01)% respectively ,which had statistical difference compared with the control group(P<0 .05) ,CD3+CD4+ lymphocyte count was (49 .98 ± 240 .2)cells/μL ,the difference was statistically significant (P<0 .05) ,CD3+ CD8+ lympho‐cytes count was (380 .9 ± 364 .6)cells/μL ,the difference was statistically significant(P<0 .05) .Conclusion The immune status in the patients with dengue fever is abnormal ,T lymphocyte percentage is significantly reduced compared with the healthy individuals .
