Correlation between fundic gland polyps and colorectal neoplasia:a case?control study

VernacularTitle:胃底腺息肉与结直肠肿瘤关系的病例对照研究
Author: Erjiong HUANG ; Wandong HONG ; Zhiming HUANG
Publication Type:Journal Article
Keywords: Gastroscopy; Colonoscopy; Fundic gland polyps; Colorectalneoplasia
From: Chinese Journal of Digestive Endoscopy 2015;32(12):825-827
CountryChina
Language:Chinese
Abstract: Objective To assess the correlation between fundic gland polyps and colorectal neoplasia. Methods Clinical records of patients who underwent both gastroduodenoscopy and colonoscopy during the same period were retrospectively analyzed. A total of 195 patients were enrolled into the study,65 diagnosed as having fundic gland polyps and 130 as controls matched with age and sex. Colonoscopic findings were compared between the two groups. Results Colorectal neoplasia was identified in 12 (18. 5%) of 65 patients and in 8 (6. 2%) of 130 controls with significant difference (P =0. 008) . Stratification analysis suggested that the incidence of colorectal neoplasia in fundic gland polyps group was higher in females or aged less than 50 than that of the control group(P=0. 023,0. 008). Conclusion Patients with fundic gland polyps have significantly higher risk for colorectal neoplasia. A screening colonoscopy may be necessary for patients with fundic gland polyps to detect colorectal neoplasia.