The target/no target ratio analysis of 18F-FDG uptaking in head and neck malignancy by SPECT/CT coincidence imaging
10.11958/58643
- VernacularTitle:头面部恶性肿瘤18F-FDG符合线路/CT显像T/N比值分析
- Author:
Nan LI
;
Xibao MAO
;
Chenmin DING
;
Wenjun BAO
;
Jing FAN
;
Ningjuan XUE
- Publication Type:Journal Article
- Keywords:
head and neck neoplasms;
neoplasm recurrence;
local;
radionuclide tomography;
single photon emission computed;
deoxyglucose;
coincidence
- From:
Tianjin Medical Journal
2016;44(1):98-101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of 18F-FDG uptaking in head and neck malignancy by SPECT/CT coincidence imaging. Methods 18F-FDG SPECT/CT coincidence imaging was performed in 32 patients with head and neck malignancy after surgery, radiotherapy or radiotherapy + chemotherapy. The radio of target/no target (T/N) was calculated. The gender, age, fasting blood glucose level, size of tumor, location of tumor, pathological classification, de-gree of cell differentiation and treatment modalities were analyzed between groups. Results The single-factor analysis of variance showed that the T/N value was significantly higher in >70 yeas old, group than that of 41-50 yeas old group and 51-60 yeas old group (P<0.05). The T/N value was significantly lower in tumor size<2 cm group than that of 2-5 cm group and>5 cm group (P<0.05). And it was lower in poor differentiated tumor group than that of. undifferentiated tumor group (P<0.05). There were no significant differences in T/N values between other indicator groups (P>0.05). The multiple linear regression analysis showed that 18F-FDG uptaking in head and neck malignancy (T/N=Y) was related to the age of patients (X2), the diameter of tumor (X4) and the degree of cell differentiation (X9): =-4.389 25+0.053 03 X2+1.617 86 X4+0.718 35 X9. Conclusion Tumor recurrence is more likely to occur in patients with age>70 years old, the diameter of tumor≥2 cm, and the anaplastic head and neck malignancy.We should pay much attention to the diagnosis and follow-up for these pa-tients.
