Effects of maternal obesity on the offspring
10.11958/58828
- VernacularTitle:母亲肥胖对后代的影响
- Author:
Yang DUAN
;
Fuqiang SUN
- Publication Type:Journal Article
- Keywords:
mothers;
obesity;
fetus;
metabolic syndromes;
offspring;
influence;
review
- From:
Tianjin Medical Journal
2016;44(1):124-126
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of maternal obesity has risen dramatically in recent years. Maternal obesity increases the risk of adverse pregnancy outcomes, and can lead to chronic inflammation, oxidative stress, the change of cell factor homeostasis. The metabolic status of maternal obesity in the pre-pregnancy and pregnancy can alter the level of DNA methylation in the placenta, change the fetal programming, influence the pregnancy outcomes, and increase the risk of obesity related metabolic syndrome and other chronic diseases of offspring. Actively preventing and intervening in the maternal obesity can reduce the adverse pregnancy outcomes and increase the survival quality of the offspring.
