Quantitative analysis of β thromboglobulin level in patients with coronary heart disease complicated dif-ferent complications
10.3969/j.issn.1008-0074.2016.02.23
- VernacularTitle:冠心病不同合并症患者中β凝血球蛋白的定量分析
- Author:
Jian XIE
;
Zhenjian ZHANG
;
Xianping HUA
;
Chuanbin CAO
;
Jin QIAN
;
Zhongxin QIN
;
Junqiu PENG
- Publication Type:Journal Article
- Keywords:
Beta-thromboglobulin;
Coronary disease;
Angina,unstable;
Brain infarction
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2016;25(2):195-197
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare serum level of β thromboglobulin in patients with coronary heart disease (CHD) complicated different complications.Methods:According to their complications,a total of 398 patients with unsta- ble angina pectoris (UAP)were divided into pure UAP group (UAP control group,n=82),hypertension group (n=89),diabetes mellitus (DM)group (n=133)and brain infarction group (n=94).Serum level of β thromboglobu- lin were measured and compared among four groups 6h after onset and before discharge.Incidence of myocardial in- farction within six months were followed up in four groups.Results:On 6h after onset,the serum level of β throm- boglobulin of brain infarction group,DM group,hypertension group,UAP control group was (61.13±3.32)ng/ml,(59.77±3.15)ng/ml,(52.12±3.27)ng/m, (48.55±3.14)ng/ml respectively,in which the level of brain infarction group was the highest,the difference between any two groups were significant (P<0.01 all);Compared with 6h after onset,there were significant reductions in serum levels of β thromboglobulin of four groups before dis- charge P<0.01 all,their ordering and difference significant degree were no change.The incidence of myocardial infarction (MI)in brain infarction group,DM group,hypertension group,UAP control group was 11.7%,6.0%, 3.4%,2.4% respectively,the MI incidence of brain infarction group was significant more than that of UAP con- trol group,the differences among other groups was no significant,P>0.05.Conclusion:β-thromboglobulin level during UAP onset is significant higher than that of remission period,and it rises most significantly in brain infarction group,and in this group the percentage of myocardial infarction occurred within six months is highest
