Research progress of mTOR signal pathway effect in cardiovascular system
10.3969/j.issn.1008-0074.2016.02.32
- VernacularTitle:mTOR信号通路在心血管系统中作用研究的进展
- Author:
Wu HONG
;
Han WEI
- Publication Type:Journal Article
- Keywords:
TOR serine-threonine kinases;
Phosphatidylinositol 3-kinases;
Cardiovascular system
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2016;25(2):225-228
- CountryChina
- Language:Chinese
-
Abstract:
Mammalian target of rapamycin (mTOR)is an atypical serine/threonine protein kinase,which is a key protein kinase regulating cell growth,proliferation,translation,metabolism and autophagy.It's first known beca- nuse inhibited by rapamycin.Research indicated that mTOR plays a key regulating role in physiological and patho- logical process of cardiovascular system.The present article mainly reviewed research progress of mTOR signal path- way effect in cardiovascular system.
