Analysis of the variability in calculating thyroid volume by SPECT imaging at different time postin-jection
10.3760/cma.j.issn.2095-2848.2016.01.016
- VernacularTitle:注射后不同时间SP ECT显像估测甲状腺体积的变异性分析
- Author:
Yanwu DONG
;
Dingquan WANG
;
Bing YAN
- Publication Type:Journal Article
- Keywords:
Thyroid;
Volume;
Tomography,emission-computed,single-photon;
Radionuclide imaging;
Technetium;
Hyperthyroidism
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2016;(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the variability of calculating thyroid volume by SPECT imaging at different time postinjection. Methods A total of 40 patients with Graves disease were enrolled in this prospective study using simple random sampling method. After intravenous injection of Na99TcmO4, all patients underwent planar and tomographic scintigraphy at different time points (5, 10, 15, 20, 25, 30, 45 and 60 min), and the planar or tomographic integral method were used to estimate thyroid volume. Data were analyzed by one?way analysis of variance, paired t test or linear correlation analysis. Results For thyroid volume esti?mated by planar imaging, the correlation coefficients between the different time points and 20 min were 0?717-0?819 (all P<0.05), and the CV was (18.38±5.31)%. For thyroid volume estimated by tomographic integral method, the correlation coefficients were 0.913-0.961 (all P<0.05), and the CV was (8.05± 3?19)%. Both the correlation coefficient and CV were statistically significant between the two methods ( t=-13.59, -11.29, both P<0.05) . Conclusions Tomographic integral method has better correlation and re?producibility in calculating thyroid volume compared with planar method.
