Effects of sevoflurane and propofol on hemodynamic changes in patients undergoing cardiac double valve replacement
10.3760/cma.j.issn.1008-6706.2016.01.029
- VernacularTitle:七氟烷与丙泊酚对心脏双瓣置换术患者血流动力学影响的比较
- Author:
Yang LI
- Publication Type:Journal Article
- Keywords:
Heartvalvereplacement;
Sevoflurane;
Propofol;
Ischemia/reperfusion;
Hemodynamics
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;(1):106-109
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effects of sevoflurane and propofol on hemodynamic changes in patients undergoing cardiac double valve replacement.Methods Totally 80 patients admitted with rheumatic heart disease were divided into sevoflurane group and propofol groups.The anesthetic drugs on hemodynamics,myocardial function and renal function were compared.Results There were statistically significant in CIL concentration,stroke volume index (SVI)and left ventricular -stroke work index (LVSWI)levels between the two groups at the same time points (F =2.467,2.4783,2.553,P =0.032,0.032,0.021).The levels of MAP,HR,PAWP,CIL,SVI and LVSWITBIL between the two groups were statistically significant at different time points (F =2.597,2.468,2.523,2.589,2.532, 2.556,P =0.032,0.021,0.030,0.021,0.024,0.023),and difference at the same group at different time points (F =2.597,2.468,2.523,2.497,2.479,2.538,P =0.032,0.021,0.030,0.034,0.034,0.038).No obvious liver and renal function damage was found during the surgery in the two groups.Conclusion Anesthesia induction of sevoflurane and propofol for patients undergoing cardiac double valve replacement has similar effects on the hemody-namics and cardiac function,without obvious damage to liver and renal function.
