Research progress of the effect of folic acid in pemetrexed-based chemotherapy
10.3760/cma.j.issn.1006-9801.2016.01.015
- VernacularTitle:叶酸在培美曲塞化疗方案中作用的研究进展
- Author:
Wenjing ZHANG
;
Yang XIA
;
Chong BAI
;
Zhuo WANG
- Publication Type:Journal Article
- Keywords:
Demetrexed;
Folic acid;
Homocysteine;
Dose
- From:
Cancer Research and Clinic
2016;28(1):61-63
- CountryChina
- Language:Chinese
-
Abstract:
This review analyzed the effect of folic acid on pemetrexed efficacy and toxicity, especially high-does folic acid supplementation. The optimal duration for supplementation prior to the first dose of pemetrexed has not been defined. The review also explored whether total plasma homocysteine levels can be as a marker to predict and avoid toxicity from pemetrexed therapy.
