Effects of Water-extracting and Concentration Process on Active Ingredients ofGanmao Tuire Granules
10.3969/j.issn.1005-5304.2016.01.022
- VernacularTitle:水煎提取及浓缩工艺对感冒退热颗粒有效成分的影响
- Author:
Beibei YANG
;
Baohua WANG
;
Ping LI
;
Wenqin JI
;
Qingqing MENG
;
Jinbo SHI
;
Lijuan LI
- Publication Type:Journal Article
- Keywords:
Ganmao Tuire Granules;
water decoction extraction;
concentration;
active ingredients
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;(1):93-95
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes in transfer rates of epigoitrin, forsythoside A and forsythin in Ganmao Tuire Granules prescription medicinal materials by water decoction extraction, vacuum concentration and atmospheric concentration.Methods Prescription medicinal materials fromGanmao Tuire Granules were decocted in water and the decoction was condensed by vacuum and atmospheric concentration process. The contents of epigoitrin, forsythoside A and forsythin at different states were measured by HPLC for transfer rates.Results The transfer rates of epigoitrin, forsythoside A and forsythin were 72.97%, 29.27%, 72.84%, respectively after decocted in water. The RSD of epigoitrin, forsythoside A and forsythin were less than 2% in the process of vacuum concentration. The transfer rates of epigoitrin, forsythoside A and forsythin by atmospheric concentration decreased by 13.51%, 7.38% and 4.24% respectively compared with vacuum concentration when concentrated to the same state.Conclusion The method for simultaneous determination of epigoitrin, forsythoside A and forsythin by HPLC has been established. A more suitable extraction and concentration process should be chosen for the preparation ofGanmao Tuire Granules.
