Early warning value of laboratory indexes for death risk in children with critical hand foot and mouth disease
10.3969/j.issn.1673-4130.2016.03.009
- VernacularTitle:实验室指标对危重型手足口病患儿死亡风险的早期预警价值
- Author:
Fei RAN
;
Yan WANG
;
Longqing ZHONG
;
Xiaoju WAN
;
Zhiqiang LIU
;
Rong DUAN
;
Jiangwei KE
- Publication Type:Journal Article
- Keywords:
critical;
hand foot and mouth disease;
death;
risk factor;
early warning value
- From:
International Journal of Laboratory Medicine
2016;(3):311-313
- CountryChina
- Language:Chinese
-
Abstract:
Objective To quantitatively analyze the early warning value of laboratory indexes for death risk in children with criti ‐cal hand foot and mouth disease (HFMD) .Methods The univariate and multivariate Logistic regression analysis were conducted to explore the independent risk factors of death in critical HFMD children .Then the area under receiver operating characteristic curve (AUC) was applied to give the comprehensive assessment of the test model ,as well as the early warning capacity and the optimal cut‐off level of laboratory indexes in critical HFMD children .Results The AUC of the Logistic regression model (Y ) established based on white blood cell ,neutrophil ,myoglobin ,creatinine for early predicting the death risk in critical HFMD children patients was 0 .847 (95% CI :0 .783 - 0 .911) ,which indicating that its diagnostic value was superior to single index .Conclusion The diag‐nostic value of the Y model established based on four indexes of white blood cell count ,neutrophile granulocytes count ,myohemo‐globin and creatinine is superior to any single index ,which has the better early warning value for the death risk in children with crit‐ical HFMD .
