Research on etiology and drug resistance analysis of ICU ventilator-associated pneumonia
10.3969/J.ISSN.1672-8270.2016.01.035
- VernacularTitle:重症监护病房呼吸机相关性肺炎的病原学及耐药性分析
- Author:
Xin ZHOU
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Ventilator-associated pneumonia;
Drug resistance;
Pathogens
- From:
China Medical Equipment
2016;13(1):111-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the etiology and drug resistance of the ICU ventilator-associated pneumonia.Methods: One hundred cases of patients with ventilator-associated pneumonia received in our ICU room were selected; the pathologic examination results were retrospectively analyzed.Results: One hundred and thirty five bacteria were isolated from 100 cases of patients with ventilator-associated pneumonia, including 95 cases of Gram-negative bacilli(70.5%), 34 cases of Gram-positive cocci(25.1%) and 6 cases of fungi(4.4%); The resistance rates of Pseudomonas aeruginosa and Klebsiella pneumoniae for cefazolin, gentamicin, levofloxacin, and trimethoprim-sulfamethoxazole were high; The resistance rate of Staphylococcus aureus for ceftazidime, ceftriaxone, cefepime, cefazolin, gentamicin, amikacin, ciprofloxacin, levofloxacin, cefoperazone/sulbactam and piperacillin were high.Conclusion: ICU ventilator-associated pneumonia pathogen was mainly Gram-negative bacteria, and showed multidrug resistance, imipenem and cefoperazone/sulbactam for most pathogens had better efficacy and worthy of clinical application.
