Research advances of M3 receptor: a new target for treating and preventing cardiovascular disease.
- Author:
Yan LIU
;
Yanjie Lü
;
Baofeng YANG
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2015;50(4):393-9
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease, with high morbidity and mortality, has been threatening the health of human beings. Therefore, expecting to find a more effective therapeutic method, a plenty of researchers devote themselves to the study of the cardiovascular disease all the time. Since discovered on the heart, M3 receptor of muscarinic acetylcholine receptor (mAchR, M receptor) became a new starting point of the research of the cardiovascular disease. With more and more investigation, many people found that M3 receptor could protect the heart from kinds of cardiovascular disease, which may make it a new hopeful therapeutic point. So, expecting to give support to the reference and encouragement for the study of disease related to M3 receptor in future, this review expounds M3 receptor on the heart from the main following aspects: the effect on the heart, the influence on the cardiovascular disease and the mechanism of M3 receptor involved.
