The importance of appling laboratory tests in diagnosing hemophagocytic lymphohistocytosis
10.3760/cma.j.issn.1009-9158.2015.11.003
- VernacularTitle:重视实验室检测对噬血细胞综合征的诊断价值
- Author:
Zhuo GAO
;
Zhao WANG
- Publication Type:Journal Article
- Keywords:
Lymphohistiocytosis,hemophagocytic;
Clinical laboratory techniques;
Killer cells,natural;
Ferritins;
Lysosomal-associated membrane protein 1
- From:
Chinese Journal of Laboratory Medicine
2015;38(11):727-729
- CountryChina
- Language:Chinese
-
Abstract:
It is a challenge in diagnosis of hemophagocytic lymphohistocytosis (HLH).Rapid diagnosis is the key to make decisions in clinical management of HLH.The timely and reliable diagnosis of HLH can be assisted by laboratory tests including nature killer (NK) cell activity, sCD25, hemophagocytosis, ferritin, surface CD107a, and genetic testing.Here is introduced lab assays and evaluate the clinical applications in HLH.The aim is to raise awareness of the values of laboratory evaluations in diagnosing HLH.