Preliminary application of real-time contrast-enhanced ultrasound in diagnosis of papillary thyroid microcarcinoma

VernacularTitle:实时超声造影技术在甲状腺微小乳头状癌诊断中的应用研究
Author: Yuemingming JIANG ; Youfeng XU ; Libin CHEN ; Feng MAO ; Jian LU ; Nan SU ; Shengmin ZHANG
Publication Type:Journal Article
Keywords: Ultrasonography; Microbubbles; Thyroid neoplasms
From: Chinese Journal of Ultrasonography 2015;24(10):882-885
CountryChina
Language:Chinese
Abstract: Objective To explore the imaging features of papillary thyroid microcarcinoma(PTMC) with real time contrast-enhanced ultrasound.Methods One hundredand forty-three cases with 149 thyroid nodules(no diffuse lession) were divided into two groups according to the diameter size(group 1,＜0.5 cm;group 2,0.5-1.0 cm) and examined by contrast-enhanced ultrasound during preoperation.Pathology was followed up as golden diagnosis criteria.Results Seventy-five benign tumors and 74 PTMC were confirmed by pathology.There were significant differences in echoes homogeneity between benign and malignant tumors in group 2(W =1 029.5,Z =-5.524,P =0.000) but no in group 1(W =933.0,Z =-1.738,P =0.082).And nonhomogeneous enhancement were showed in most PTMC in group 2.But most PTMC showed homogeneous enhancement in group 1.Conclusions Contrast-enhanced ultrasound is valuable in diagnosis of PTMC with the diameter size of 0.5-1.0 cm.