The treatment of liver metastases of gastroentero-pancreatic neuroendcorine neoplasms
10.3760/cma.j.issn.1007-631X.2015.11.011
- VernacularTitle:胃肠胰腺神经内分泌肿瘤合并肝转移的治疗
- Author:
Qiang HUANG
;
Chenglin ZHU
;
Xiansheng LIN
;
Chenhai LIU
;
Yuanguo HU
;
Cheng WANG
;
Lujun QIU
- Publication Type:Journal Article
- Keywords:
Neuroendcorine tumors;
Neoplasm metastasis;
Liver transplantation
- From:
Chinese Journal of General Surgery
2015;30(11):879-881
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the treatment of gastroentero-pancreatic neuroendcorine neoplasms with liver metastasis.Methods Two gastroentero-pancreatic neuroendcorine neoplasms with liver metastases treated at Anhui Provincial Hospital Affliated of Anhui Medical University were analyzed retrospectively.Results In first patient liver metastases from duodenal papilla neuroendocrine neoplasm was treated by four courses of TACE until the liver metastases completely disappeared.The patient then underwent pancreaticoduodenectomy to eradicate the primary tumor.The patient was followed up for 2 years and was doing well.In second patient, liver metastasis, noted four years after distal pancreatectomy for a neuroendocrine tumor, was initially managed by high dosage of octreotide and sunitinib.After these attempts failed, the patient received a liver transplantation four years ago and was followed up until March 1, 2015 without tumor recurrence.Conclusion Liver metastasis of gastroenteropancreatic neuroendcorine neoplasms responds positively to liver transplant with pretty good prognosis.
