Diagnosis of acute kidney injury and its biomarkers in children
10.3760/cma.j.issn.1673-4408.2015.06.011
- VernacularTitle:儿童急性肾损伤诊断标准及生物标志物研究进展
- Author:
Lei SUN
- Publication Type:Journal Article
- Keywords:
Acute kidney injury;
Children;
Diagnosis;
Biomarker
- From:
International Journal of Pediatrics
2015;42(6):639-643
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury (AKI)was a common problem in children in clinic.pRIFLE Criteria, AKIN Criteria, KDIGO Criteria are the main classification criteria of AKI.Though serum creatinine is still used as the most common biomarkers for diagnosis of AKI, the sensitivity and specificity is unsatisfactory.In recent years, many potential biomarkers of AKI have been studied in a variety of experimental and clinical settings.This review describes the novel biomarkers of AKI, including cystatin C, neutrophil gelatinase associated lipocalin, interleukin-18 ,kidney injury molecule-1 and liver-type fatty acid binding protein,, which have now made a progress in clinic.
