Research progress of fatty acid synthase in cancer
10.3760/cma.j.issn.1006-9801.2015.10.019
- VernacularTitle:脂肪酸合酶在肿瘤中的研究进展
- Author:
Xin LI
- Publication Type:Journal Article
- Keywords:
Cancer;
Fatty acid synthase;
Resistance mechanism
- From:
Cancer Research and Clinic
2015;27(10):717-720
- CountryChina
- Language:Chinese
-
Abstract:
Fatty acid synthase (FAS) can be regarded as a tumor-specific therapeutic target.High expression of FAS is found in many tumor tissues, and inhibition of its expression can induce tumor cell death.Recent researches has shown that FAS can be used not only as the target of tumor therapy, but also as a tumor marker.The serum FAS is higher in cancer patients.High expression of FAS is associated with tumor treatment tolerance, and some new inhibitors for FAS show good anti-cancer effects.
