Long-term effect of peroral endoscopic myotomy on achalasia in pediatric patients
10.3760/cma.j.issn.1007-5232.2015.08.010
- VernacularTitle:经口内镜下环形肌切开术治疗儿童贲门失弛缓症的远期疗效观察
- Author:
Ying FANG
;
Xiaoxia REN
;
Hongbin YANG
;
Zhiguo LIU
;
Pinghong ZHOU
- Publication Type:Journal Article
- Keywords:
Achalasia;
Peroral endoscopic myotomy;
Pediatric patient
- From:
Chinese Journal of Digestive Endoscopy
2015;32(8):544-548
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility, safety and the efficacy of peroral endoscopic myotomy (POEM) for pediatric patients with achalasia.Methods A total of 21 patients (mean age 2 years, range 11 months-7 years) with AC were enrolled and underwent POEM from January 2012 to December 2014.Procedure-related complications, reflux esophagitis were observed.Eckardt score and the pressure of the lower esophageal sphincter (LES) were analysed.Results All patients underwent POEM successfully.No serious POEM-related complications were observed.During a mean follow-up period of 20.4 months (range 9-36 months), mean Eckardt score decreased from 8.1 to 0.8 after treatment (P < 0.01).Mean LES treatment also decreased from 30.2 mmHg to 11.5 mmHg after the operation (1 mmHg =0.133 kPa, P < 0.01).Reflux esophagitis developed in four patients (19.0% ,4/21).Conclusion POEM is safe and effective treatment for pediatric patients with achalasia.