Long-term effect of peroral endoscopic myotomy on achalasia in pediatric patients

VernacularTitle:经口内镜下环形肌切开术治疗儿童贲门失弛缓症的远期疗效观察
Author: Ying FANG ; Xiaoxia REN ; Hongbin YANG ; Zhiguo LIU ; Pinghong ZHOU
Publication Type:Journal Article
Keywords: Achalasia; Peroral endoscopic myotomy; Pediatric patient
From: Chinese Journal of Digestive Endoscopy 2015;32(8):544-548
CountryChina
Language:Chinese
Abstract: Objective To explore the feasibility, safety and the efficacy of peroral endoscopic myotomy (POEM) for pediatric patients with achalasia.Methods A total of 21 patients (mean age 2 years, range 11 months-7 years) with AC were enrolled and underwent POEM from January 2012 to December 2014.Procedure-related complications, reflux esophagitis were observed.Eckardt score and the pressure of the lower esophageal sphincter (LES) were analysed.Results All patients underwent POEM successfully.No serious POEM-related complications were observed.During a mean follow-up period of 20.4 months (range 9-36 months), mean Eckardt score decreased from 8.1 to 0.8 after treatment (P ＜ 0.01).Mean LES treatment also decreased from 30.2 mmHg to 11.5 mmHg after the operation (1 mmHg =0.133 kPa, P ＜ 0.01).Reflux esophagitis developed in four patients (19.0％ ,4/21).Conclusion POEM is safe and effective treatment for pediatric patients with achalasia.