Clinical values of hypothyroidism and subclinical hypothyroidism screening in pregnancy

VernacularTitle:妊娠合并甲状腺功能减退和亚临床甲状腺功能减退筛查的临床意义
Author: Chunhong SONG
Publication Type:Journal Article
Keywords: Hypothyroidism; Pregnancy
From: Chinese Journal of General Practitioners 2015;14(8):620-622
CountryChina
Language:Chinese
Abstract: To explore the significance of hypothyroidism and subclinical hypothyroidism screening in pregnancy.A total of 278 pregnant women were divided into three groups of clinical hypothyroidism (n =36),subclinical hypothyroidism (n =103) and normal control (n =139).Their clinical profiles,pregnancy outcomes and fetal status were analyzed.The incidences of abortion (11.1％),premature delivery (8.3％),preeclampsia (11.1％),gestational diabetes mellitus (GDM,13.9％),anemia (16.7％),fetal distress (8.3％) and fetal growth retardation (FGR,5.6％) in clinical hypothyroidism group were higher than those in normal control group (2.9％,1.4％,1.4％,2.2％,4.3％,0.0％ and 3.6％).And the differences were statistically significant (P ＜ 0.05).The incidence of adverse pregnancy had a significant correlation with hypothyroidism in pregnant women.Therefore screening of thyroid functions is essential for improving pregnancy outcomes of pregnant women with hypothyroidism.