Early respiratory infections in lung transplantation recipients from donation after cardiac death donors
10.3760/cma.j.issn.0254-1785.2015.05.002
- VernacularTitle:器官捐赠供肺移植受者术后早期肺部感染17例临床分析
- Author:
Bo WU
;
Ji ZHANG
;
Dong WEI
;
Jingyu CHEN
- Publication Type:Journal Article
- Keywords:
Lung transplantation;
Respiratory infectious
- From:
Chinese Journal of Organ Transplantation
2015;36(5):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the epidemiology,etiology and prevention strategy of early respiratory infections (≤1 month) in lung transplantation recipients with donation after cardiac death donors.Method The clinical data of donors and recipients,particularly on early respiratory infections,were retrospectively analyzed in 17 lung transplantations.Result From Jan.2015 to Apr.2015,12 episodes of early respiratory infections (≤ 1 month) in 17 lung transplantation recipients occurred (12/17,70.6％).The organisms most frequently involved were bacteria:Pseudomonas aeruginosa (4/26,15.4％),Klebsiella pneumoniae (4/26,15.4％),Staphylococcus aureus (3/26,11.5％),and Acinetobacter baumannii (3/26,11.5％).Of 26 bacterial strains,3 were Methecillin resistant Staphlococcus aureus,3 were carbapenem resistant Acinetobacter baumanni,2 were carbapenem resistant Pseudomonas cepacia,2 were extended spectrum b-lactamase-producing Klebsiella pneumoniae,and one was carbapenem and quinolone resistant Pseudomonas aeruginosa.Conclusion The morbidity of early infections is high in lung transplantation recipients.In our experience,bacterial respiratory infections are most common in the early post-transplant period (≤ 1 month).Incidence of Aspergillus spp.and Cytomegalovirus pneumonia is lower than before lung transplantation,probably due to the spread of universal prophylaxis.
