Role of periostin in bone metabolism
10.3760/cma.j.issn.1000-6699.2015.11.016
- VernacularTitle:骨膜蛋白在骨代谢中的作用
- Author:
Shidi HU
;
Xin LI
;
Lu LIU
;
Ruchun DAI
- Publication Type:Journal Article
- Keywords:
Periostin;
Osteoblasts;
Fracture;
Bone remodelling;
Bone turnover
- From:
Chinese Journal of Endocrinology and Metabolism
2015;31(11):995-999
- CountryChina
- Language:Chinese
-
Abstract:
Periostin is preferentially expressed in the periosteum, which covers a large majority of bones.Periostin has been reported to promote osteoblast proliferation, adhesion, and differentiation, involving bone repair process, response to mechanical stimulation and parathyroid hormone (PTH), regulating bone development/ remodeling and bone strength.Circulating periostin may serve as a candidate of biological markers for bone metabolism.
