Analysis of urate crystal deposition us ing dual-source CT in asymptomatic hyperuricaemia and symptomatic gout patients
10.3760/cma.j.issn.1007-7480.2015.010.009
- VernacularTitle:无症状高尿酸血症患者及痛风患者四肢关节尿酸盐结晶的双源CT对比分析
- Author:
Liuhui CHENG
;
Daoqing WANG
;
Baopeng ZHANG
;
Suogang WANG
;
Zhou ZHOU
;
Zeying WEN
- Publication Type:Journal Article
- Keywords:
Gout;
Hyperuricemia;
Tomography,spiral computed;
Uric acid
- From:
Chinese Journal of Rheumatology
2015;19(10):686-689
- CountryChina
- Language:Chinese
-
Abstract:
Objective Retrospectively analyze of urate crystal deposition using dual-source CT in asymptomatic hyperuricaemia and symptomatic gout patients.Methods Sixty patients with asymptomatic hyperuricemia (uric acid ≥540 μmol/L) and 48 patients with gout (without any change in the appearance of the limbs and obvious gout nodules) were selected.All patients underwent dual-energy CT imaging.The location number and size were analyzed using CT gout software.Results Eighteen patients with asymptomatic hyperuricemia with urate crystal deposition in limb joints (13 in foot and ankle, 7 in the hand and wrist, 2 in knee), the average size of crystal was (0.12±0.04) cm3.Forty-eight gout patients (28 cases of early gout and 20 cases of late gout and 20 gout cases) had urate crystal deposition (48 in foot and ankle, 39 in hand and wrist, 27 in knee), the average size of crystal was (1.7±0.7) cm3.The number and size of urate crystals deposited in the joints, tendons and ligaments was higher in patients with gout than asymptomatic hyperuricemia (x2=52.076, P＜0.001;t=44.834, P＜0.001).There was no difference between the early gout and late gout in the size of urate crystals (t=0.163, P＞0.05).Conclusion Urate crystals can deposite in asymptomatic hyperuricemia.However, more and larger urate crystals appear in gout patients, there is no difference in size and number of urate crystals between the course duration of gout.
