Analysis of sublingual misoprostol on planned delivery with full-term pregnancy
10.3760/cma.j.issn.1008-6315.2015.09.024
- VernacularTitle:颊黏膜含化米索前列醇在足月妊娠计划分娩中的应用
- Author:
Huili LI
;
Rui LI
- Publication Type:Journal Article
- Keywords:
Misoprostol;
Planned delivery;
Outcomes of pregnancy;
Cervical ripening
- From:
Clinical Medicine of China
2015;31(9):849-851
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effect of sublingual misoprostol on planned delivery with full-term pregnancy and influence on outcomes of pregnancy and newborns.Methods Ninety-six puerpera with cervical bishop score ≤ 4 were randomly divided into the control group(n =48) and research group (n =48).The patients of the control group were given oxytocin therapy while the research group were given sublingual misoprostol.The promoting effect of cervical maturity,induced abortion effects,outcomes of pregnancy and newborns between the two groups were compared.Results The total effective rate of cervical maturity of research group was obviously higher than that of control group,the differences were statistically significant (91.7％ (44/48) vs 66.7％ (32/48),x2=7.834,P =0.015).The total effective rate of induced abortion effects of research group was obviously higher than that of control group,the differences were statistically significant (93.8％ (45/48) vs 54.2％ (26/48),x2=9.653,P=0.004).The postpartum hemorrhage((183.6±24.2) ml vs.(216.5±32.6) ml,t=6.748),total stageoflabor((7.6±1.3) h vs.(11.3±2.5) h,t=6.636) and cesarean section rate(31.3％ vs.47.9％,x2 =5.637) of research group was obviously lower than that of control group,the differences were statistically significant (P＜0.05).Two groups of newborns and the incidence of neonatal asphyxia,amniotic fluid pollution had no statistically significant difference(P＞0.05).Conclusion The clinical effect of sublingual misoprostol on.planned delivery with full-term pregnancy is obvious and causes little influence on outcomes of pregnancy and newborns.It is safe and effective to be applied on planned delivery and worth popularization and application.
