Ultrasonic features of triple-negative breast cancer
10.3760/cma.j.issn.1008-1372.2015.08.021
- VernacularTitle:三阴性乳腺癌超声特征探讨
- Author:
Shichu TANG
;
Zhiyuan WANG
;
Tao OUYANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms/US;
Ultrasonography,doppler,color
- From:
Journal of Chinese Physician
2015;17(8):1197-1199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the ultrasonic features of triple-negative breast cancer (TN-BC).Methods Ultrasonographic findings of 299 patients with pathologically confirmed breast cancer were analyzed retrospectively.Patients were divided into TNBC group (46 cases) and non-triple-negative breast cancer(NTNBC) group (253 cases) according to the expression of estrogen receptor (ER),progesterone receptor (PR),and human epidermal growth factor receptor 2 (HER2) that were determined with immunohistochemical staining.Each patient was ultrasonically analyzed.Results The ultrasonic images showed that TNBC group had a greater proportion in the mass with regular shape,clear boundary,or microlobulated relative to NTNBC group (P ＜ 0.01).Calcification was significantly less in TNBC than NTNBC (P ＜0.01).Eight (17.3％)of 46 Cases of TNBC had BI-RADS sonographic features that favored the diagnosis of a benign condition.Conclusions Some of sonographic criteria for TNBC are more likely to be associated with benign lesions,ultrasound-guided biopsy should be recommended for such lesions.
