Research Overview and Question Discussion on International Clinical Phenotype Ontology

VernacularTitle:国际临床表型的本体研究概述及问题探讨
Author: Lin LIU ; Xuezhong ZHOU ; Xiaji ZHOU ; Runshun ZHANG ; Yufeng GUO ; Yinghui WANG ; Qi XIE ; Baoyan LIU
Publication Type:Journal Article
Keywords: Traditional Chinese medicine clinical symptom; individual diagnosis and treatment; precision medicine; traditional Chinese medicine clinical phenotype; integrated ontology
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(8):1634-1638
CountryChina
Language:Chinese
Abstract: Traditional Chinese medicine (TCM) clinical symptoms, which were main evidences in syndrome differentiation and treatment, were also main data in the clinical individual diagnosis and treatment. However, the absence of high-quality symptom ontology was still obvious in TCM clinical and data using. By analyzing the research and data of clinical phenotype ontologies associated with symptoms, this paper was aimed to introduce and sort the existing ontologies, in order to discuss related problems. Furthermore, we provided ideas and expound the importance of building data network of symptoms, diseases, genes, drugs, chemicals, side effects with the data we collected and disposed around symptoms, in order to construct TCM clinical phenotype ontology. We believed that our work will help the development of individual treatment and precision medicine in TCM. It was also the key of individual big data analysis which was urgent need to promote.