Analysis on the infection and drug susceptibility of mycoplasma in 1 9 530 cases of urogenital tract infections
10.3969/j.issn.1671-8348.2015.25.028
- VernacularTitle:19530例泌尿生殖道感染患者支原体感染及药敏结果分析
- Author:
Ya GONG
;
Deling DUAN
;
Zongzhong HE
;
Xiaodong WANG
;
Qiuxia SHI
;
Lindong LIN
;
Weihua OU
- Publication Type:Journal Article
- Keywords:
mycoplasma;
urogenital tract;
drug susceptibility test;
drug resistance rate;
multiple drug resistance
- From:
Chongqing Medicine
2015;(25):3539-3541
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the status of mycoplasma infection and drug resistance in the local area,and provide the ba-sis for clinical rational drug use.Methods The specimens obtained from 1 9 530 patients with urogenital tract infection were detec-ted by adopting mycoplasma culture,identification and drug sensitivity integration kit.Mycoplasma infection and drug susceptibility were analyzed.Results In the total of 1 9 530 suspected patients specimens,1 1 1 78 cases were positive with a positive rate 57.24%.The positive rate of ureaplasma urealyticum (Uu)and mycoplasma hominis (MH)was 44.63% and 0.44% respectively and the positive rate of Uu and Mh mixed infection was 12.1 7%.The positive rate of female was higher than that of male and the difference was statistically significant(P <0.05).The positive rate of mycoplasma in 2008-2014 was on the rise;The sensitive rate of mycoplasma to josamycin,doxycycline,minocycline element,clarithromycin was 88.57%,84.32%,76.09% and 71.53% respec-tively,mycoplasma was highly drug resistance to quinolone antibiotics;mixed infection resistance was higher than that of single in-fection;The number of drug resistance of Uu,MH and Uu+MH to 12 kinds of antibiotics increase.Conclusion Mycoplasma infec-tion in urogenital tract is mainly caused by Uu and Mh infection is in mixed infection way;josamycin,doxycycline is the first choice for treatment of mycoplasma in this region.Rational drug choise can be based on the drug susceptibility test.Multiple drug resist-ance of mycoplasma is serious and should be paid attention to.
