Transfusion efficacy and safety evaluation in patients with non-specificity irregular antibody
10.3969/j.issn.1673-4130.2015.18.006
- VernacularTitle:不规则抗体特异性不明确患者的输血疗效及安全性评估
- Author:
Lu YANG
;
Linfeng CHEN
;
Yang YU
;
Yan WANG
;
Xiaozhen GUAN
;
Xiaolin SUN
;
Xiaojuan ZHANG
;
Jinhui WANG
;
Deqing WANG
- Publication Type:Journal Article
- Keywords:
irregular antibody;
antibody specificity;
transfusion efficacy;
transfusion safety
- From:
International Journal of Laboratory Medicine
2015;(18):2630-2632
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the transfusion efficacy and safety of patients with non‐specificity irregular antibodies .Meth‐ods A total of 19 cases of patients with non‐specificity irregular antibodies were analyzed ,then the transfusion efficacy and the in‐cidences of adverse transfusion reactions were investigated .Blood donor samples with the same ABO blood type of patients were randomly collected ,then blood cross‐matching was carried out .And the transfusion efficacy and safety of patients with non‐specific‐ity irregular antibody were evaluated when compatible blood were found by using both micro‐column gel technique and saline meth‐od .Results The non‐specificity irregular antibodies of the 19 cases of patients all were IgG irregular antibodies .The erythrocyte transfusion was carried out in the 19 cases of patients ,the total efficiency rate ,partial efficiency rate and inefficiency rate was 73 .7% ,26 .3% and 0 .0% ,respectively .No delayed hemolytic transfusion reactions were observed in any patient .Conclusion For patients with non‐specificity irregular antibodies ,the blood transfusion could be efficacy and safety when compatible blood samples are confirmed by using both micro‐column gel technique and saline method .