Application value of combined detection of procalcitonin and high-sensitivity C-reactive protein in the diagnosis of infectious diseases
10.3969/j.issn.1673-4130.2015.18.036
- VernacularTitle:降钙素原和超敏C反应蛋白联合检测在感染性疾病中的应用价值
- Author:
Tianxiang LONG
;
Jinxing CHEN
;
Xiaodong HUANG
;
Futong LIN
- Publication Type:Journal Article
- Keywords:
infectious diseases;
procalcitonin;
high-sensitivity C-reactive protein
- From:
International Journal of Laboratory Medicine
2015;(18):2704-2705
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore application value of combined detection of procalcitonin(PCT ) and high‐sensitivity C‐reactive protein (hs‐CRP) in clinical diagnosis of infectious diseases .Methods 162 cases of hospitalized patients with infectious diseases from June 2012 to December 2014 were enrolled in this study and divided into bacterial infection group(92 cases)and viral infection group (70 cases) according to the results of isolation and culture of pathogen and virus antibody detection .Other 100 cases of healthy individuals were selected as healthy control .The serum levels of PCT and hs‐CRP were detected by using immunochroma‐tography and immunofluorescence assay respectively and were statistically analysed .Results The serum levels of PCT and hs‐CRP in the bacterial infection group were higher than those in the healthy control group ,the differences were statistically significant (P<0 .05) .The serum levels of PCT and hs‐CRP in the viral infection group were higher than those in the healthy control group , but only the difference of hs‐CRP between the two groups was statistically significant(P<0 .05) .In patients with bacterial infection and viral infection ,the positive rates of combined detection of hs‐CRP and PCT were higher than single detection of hs‐CRP or PCT ,the differences were statistically significant(P<0 .05) .Conclusion PCT and hs‐CRP could be important serum markers of bacterial infections ,combined detection of the two markers have clinical significance for diagnosing infectious diseases and assessing its prognosis .
