Correlation of TIMI to NTpro-BNP and TNⅠ in acute coronary syndrome patients
10.3969/j.issn.1671-8348.2015.25.031
- VernacularTitle:急性冠状动脉综合征患者 TIMI 危险评分与血浆 NTpro-BNP、TNⅠ的相关性研究
- Author:
Bharti NUR
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome;
plasma N terminal pro brain natriuretic peptide;
serum troponin Ⅰ
- From:
Chongqing Medicine
2015;(25):3547-3549
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the correlation TIMI risk score to plasma N terminal pro brain natriuretic peptide(NTpro-BNP)level and serum troponin Ⅰ(TNⅠ)in patients with acute coronary syndrome.Methods Totally 98 cases of acute coronary artery from May,2013 to September,2014 treated in our hospital with syndrome TIMI risk score were observed,According to the score,the patients were divided into low risk group(n=23),middle risk group(n=34)and high risk group(n=41),and NTpro-BNP and TNⅠ levels were detected by AQT rapid immunoassay.The correlation of TIMI and NTpro-BNP and TNⅠ were stud-ied..Results TIMI scores in single,double,triple disease have statistically significant differences(P <0.01).The adverse event in-cidence of the high risk group was higher than the middle risk group and the low risk group(P <0.01).TIMI risk score was effec-tive in predicting adverse cardiovascular events,patients in the 3 groups after 6 months of treatment all had higher incidence of ad-verse events than that of the 3 month and the treatment period,the incidence of adverse events in high risk group was significantly higher than that in low risk group and middle risk group(P <0.01).Low risk group,the middle group,the high risk group of pa-tients with the increase of TIMI risk score,NTpro-BNP and BNP levels were elevated,NTpro-BNP increases more significantly,can be used to identify high risk patients,(P <0.01).Spearman rank correlation analysis shows that NTpro-BNP was relation to TIMI (P <0.01),and NTpro-BNP had positive correlation with TNⅠ(P <0.05);TIMI no statistically significant correlation with TNⅠ(P >0.01).Conclusion TIMI risk score in patients with acute coronary syndromes has significant correlation with NTpro-BNP, but has no correlation with TNⅠ.
