The drug resistance situation and clinical distribution of multi-drug resistance Acinetobacter baumannii in a general hospital in 2014
10.3969/j.issn.1673-4130.2015.18.013
- VernacularTitle:2014年某综合性医院多药耐药鲍曼不动杆菌的耐药现状及临床分布
- Author:
Xidi CHI
;
Shihua GAO
;
Mengyun CHEN
;
Jialong CHEN
;
Rongjin LIN
- Publication Type:Journal Article
- Keywords:
multi-drug resistance;
Acinetobacter baumannii;
clinical distribution;
drug resistance
- From:
International Journal of Laboratory Medicine
2015;(18):2647-2649
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the drug resistance situation and clinical distribution of multi‐drug resistance Acinetobacter baumannii(MDRAB) ,in order to provide references for clinical treatment and prevention of MDRAB infection .Methods The de‐partments ,types of specimens ,time of infection ,gender and age of patients with Acinetobacter baumannii(AB)infection from Janu‐ary to December 2014 were retrospectively analysed ,and drug resistance rates of MDRAB were analysed as well .Results A total of 123 strains of MDRAB were isolated ,which accounted for 44 .73% of all strains of AB .The antibacterial resistance rates were over 90% for MDRAB against 12 out of 15 common antibacterial agents ,while the antibacterial resistance rate for MDRAB against mi‐nocycline was relatively low(19 .23% ) .Distribution of AB and MDRAB infection concentrated to certain departments ,which shown that intensive care unit(ICU) ,departments of respiratory medicine and neurosurgery were the major departments of infection .The strains of AB and MDRAB isolated from sputum specimens accounted for 84 .00% and 93 .50% respectively .There was no signifi‐cant differences of MDRAB infection among 12 Months in 2014 .There was no statistically significant differences in constituent ratio of MDRAB infection and non‐MDRAB infection between patients in different gender and between patients in different age groups . Conclusion MDRAB strains are seriously resistant to commonly used antibacterial agents ,while minocycline could still be a signifi‐cant antibacterial agent for clinical treatment of MDRAB infection .Strengthening infection management in ICU and departments of respiratory medicine and neurosurgery ,and infection management of respiratory tract and wound could have significance for reduc‐ing the risk of MDRAB infection .
