Antibacterial Activity Observation of TGC, MH and PB on the Pan-resistant Acinetobacter Baumannii in Vitro

VernacularTitle:TGC，MH 和 PB 对泛耐药鲍曼不动杆菌的体外抗菌活性观察
Author: Hua ZHANG ; Jie ZHAN ; Jinrong CANG ; Zi FU ; Qiaodi GUI ; Ying LIU ; Miao CHEN ; Yanyan GONG
Publication Type:Journal Article
Keywords: tigecycline; minocycline; polymyxin B; pan-resistant Acinetobacter baumannii; vitro antibacterial activity
From: Journal of Modern Laboratory Medicine 2015;(4):93-95
CountryChina
Language:Chinese
Abstract: Objective To observe tigecycline (TGC),minocycline (MH)and polymyxin B (PB)in vitro antibacterial activity of pan-resistant Acinetobacter baumannii (PDR-Ab)for clinical treatment,provide the basis for infection control.Methods Collected 76 patients’clinical specimens used for no repeat count of isolation and identification with pan-resistant Acineto-bacter baumannii in Shaanxi Provincial People’s Hospital from October 2013 to March 2013.Used tigecycline,minocycline and polymyxin B to do susceptibility testing with disk diffusion method (KB).Results 76 pan-resistant Acinetobacter bau-mannii ,sensitive to the rate for tigecycline and polymyxin B were 100% sensitivity rate of minocycline and intermediary rates were 67.11%,27.63%.Conclusion Tigecycline,minocycline and polymyxin B for the Pan-resistant Acinetobacter bau-mannii had good in vitro antibacterial activity.It provide a reference for clinical pan-resistant Acinetobacter baumannii infec-tions caused by diseases treatment.