Safety and Efficacy of Adopting Different Vascular Access During Autologous Peripheral Blood Stem Cells Collection
10.3969/j.issn.1671-7414.2015.04.032
- VernacularTitle:采用不同血管通路采集自体外周血造血干细胞的安全性及有效性评估
- Author:
Jin CHEN
;
Caili GUO
;
Chunhong SUN
;
Fang LIU
;
Yan WANG
;
Xiaoning WANG
- Publication Type:Journal Article
- Keywords:
stem cell collection;
double cavity of femoral vein catheter;
mononuclear cells
- From:
Journal of Modern Laboratory Medicine
2015;(4):111-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the safety and efficacy of adopting different vascular access during autologous peripheral blood stem cells collection.Methods 87 patients received autologous peripheral blood stem cells collection were divided into two groups:One was peripheral vein harvesting group (43 cases),which used the 16G disposable fistula needle for autolo-gous peripheral blood stem cell collection and the other central venous harvesting group (44 cases),which used double cavity of femoral vein catheter for autologous peripheral blood stem cell collection.The observation indicators included venous ac-cesses,collection efficiency,patient tolerance,the number of mononuclear cell and CD34 positive cells.Results The numbers of mononuclear cells and CD34 positive cells in two groups were all above the standard and there was no significant differ-ence (P >0.05).However,the success of venous accesses,the efficiency smooth of collection and-patient tolerance were bet-ter in double cavity of femoral vein catheter group (P <0.05).Conclusion Harvesting the autologous peripheral blood stem cell through central venous by using double cavity of femoral vein catheter had the advantages as follows:high success rate of puncture,acquisition smoothly and reducing the suffering extent of the patients,and also it did not affect the acquisition effi-ciency and effectiveness.
