Discussing the Correlation between BA,EMAb, ACA and Unexplained Recurrent Spontaneous Abortion
10.3969/j.issn.1671-7414.2015.04.042
- VernacularTitle:探讨 BA，EMAb 及 ACA与不明原因复发性自然流产的相关性
- Author:
Liuqing CHEN
;
Jufei LIAN
;
Li ZENG
;
Kefeng LAI
;
Zhu LIN
- Publication Type:Journal Article
- Keywords:
blocking antibodies;
antiendometrial antibodies;
anticardiolipin antibodies;
unexplained recurrent spontaneous abor-tion
- From:
Journal of Modern Laboratory Medicine
2015;(4):137-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the correlation between the joint detection of BA,EMAb,ACA and unexplained recurrent spontaneous abortion(URSA).Methods Selected 144 URSA cases,166 SA(sporadic abortion)cases,188 normal pregnant women,and detected their BA,EMAb,ACA and statistical analysis of parallelism.Results Comparing URSA group with SA group and control group respectively,there were significant statistical difference between BA negative rate (74.31%, 25.30% and 50.53%),EMAb positive rate (35.42%,7.23% and 6.91%)and ACA positive rate (26.39%,5.42% and 5.32%)(χ2 = 19.344 ~ 74.180;P < 0.05;χ2 = 37.837 ~ 42.586,P < 0.05),(χ2 = 26.355 ~ 29.270,P < 0.05).URSA group’s BA,ACA and EMAb joint detection rate of positive (84.72%)was significantly higher than SA group and the con-trol group (χ2 =35.532~93.076,P <0.05).Conclusion There was a close relationship between the lack of BA,the genera-tion of EMAb,ACA and unexplained recurrent spontaneous abortion.Joint detection has important clinical significance in auxiliary diagnosis of unexplained recurrent spontaneous abortion and prognosis judgement.
