Evaluation on the Effect of Serum CEA,Ferritin and Plasma D-D on Lung Cancer Chemotherapy
10.3969/j.issn.1671-7414.2015.04.044
- VernacularTitle:血清 CEA，Ferritin 和血浆 D-D对肺癌化疗的效果评估
- Author:
Jing ZHU
;
Haijun ZHAI
- Publication Type:Journal Article
- Keywords:
carcinoembryonic antigen;
ferritin;
D-dimer;
chemotherapy of lung cancer
- From:
Journal of Modern Laboratory Medicine
2015;(4):144-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate changes in the level of serum CEA,Ferritin and plasma D-D of the lung cancer patients suffering before and after the chemotherapy,and evaluate its application value in judging the curative effect of chemotherapy on the lung cancer patients.Methods Chose 120 lung cancer patients diagnosed from September 2011 to September 2014, and determined the curative effect in accordance with the standard for evaluating the curative effect of solid tumors set down by WHO.Chose another group of 120 healthy physical examinees as its control group.Tested the contents of serum CEA, Ferritin and plasma D-D of both groups respectively and analyzed the rules of change in the results of the patients before and after chemotherapy and in different chemotherapeutic effect stages.Results The contents of serum CEA,Ferritin and plas-ma D-D of the lung cancer patients were obviously higher than those of such patients after chemotherapy and those of the control group,and the difference was of statistical significance (t=4.123~14.224,P <0.05).The contents of serum CEA, Ferritin and plasma D-D of the patient at complete remission (CR)stage were lower than those at partial remission (PR) stage,stable disease (SD)stage and progress disease (PD)stage,and the difference was of statistical significance (t=4.230~12.336,P <0.05).Conclusion The test on the serum CEA,Ferritin and plasma D-D of the lung cancer patients before and after chemotherapy is of certain clinical value and the change in their content levels can be taken as a reference index for the chemotherapeutic effect of lung cancer patients.
