Effect of acid-suppressive drugs on laryngeal contact granuloma

VernacularTitle:抑酸药物治疗喉接触性肉芽肿
Author: Shiyu TIAN ; Jinrang LI
Publication Type:Journal Article
Keywords: Granuloma,Laryngeal; Drug Therapy; proton pump inhibitor; acid suppression
From: Chinese Archives of Otolaryngology-Head and Neck Surgery 2015;(9):438-441
CountryChina
Language:Chinese
Abstract: [ABSTRACT]OBJECTIVETo assess the efficacy of proton pump inhibitor (PPI) on the treatment for laryngeal contact granuloma.METHODSSixty seven patients with laryngeal contact granuloma who were diagnosed in our department from March 2010 to October 2014 were enrolled in this study and all patients received PPI therapy, meanwhile the clinical data of the patients was analyzed. The follow-up period was at least half a year.RESULTS The 67 patients were treated well with the PPI. Fifty patients were cured, 11 patients were obvious improved, 4 patients were improved and 2 patients were invalid. The total efficacy rate was 97.01%. The average time of PPI used in small lesion group was shorter than that in large lesion group.CONCLUSIONPPI is effective for laryngeal contact granuloma, it can be recommended the first choice for the treatment of the disease.