Effects Analysis of Joint Function and MMP-7 and MMP-9 Measurement after Synovial Arthroscopic Debridement for Knee Synovitis
10.3969/j.issn.1671-7414.2015.04.011
- VernacularTitle:膝关节滑膜炎滑膜清理术前后MMP-7与 MMP-9测定和关节功能的影响分析
- Author:
Jihong ZHANG
;
Xiaojuan WANG
;
Hongsheng DANG
;
Wuzhou WU
;
Bo WANG
;
Cao CUI
;
Haibing ZOU
- Publication Type:Journal Article
- Keywords:
arthroscopy;
synovial debridement;
knee synovitis;
nervous system
- From:
Journal of Modern Laboratory Medicine
2015;(4):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effects analysis of joint function and MMP-7 and MMP-9 measurement after synovial ar-throscopic debridement for knee synovitis.Methods 72 patients with knee synovitis method based on a random draw were e-qually divided into the treatment group and the control group,the control group were given the traditional synovial planing surgery.The treatment group were given the arthroscopic debridement synovium.Results After treatment,the response rates in the treatment group and the control group were 97.2% and 80.6% respectively.The response rate of the treatment group were significantly better than the control group.The difference was statistically significant (P <0.05).The postopera-tive Lysholm scores were increased significantly,while the pain scores were significantly reduced,and the postoperative Ly-sholm score and pain scores difference compared between the two groups were also statistically significant.The difference was statistically significant (P <0.05).The postoperative synovial tissue MMP-7 and MMP-9 expression rates were in the two groups significantly lower.The difference was statistically significant (P <0.05),while the postoperative MMP-7 and MMP-9 expression rates of the treatment group were ignificantly lower than the control group (P <0.05).Conclusion Syn-ovial arthroscopic debridement for knee synovitis can relieve pain and improve knee function,reduce the expression of MMP-7 and MMP-9,thereby enhance the overall efficacy of the treatment.
