Expression and significance of HA117 gene in tumor
10.3760/cma.j.issn.1673-422X.2015.10.007
- VernacularTitle:HA117基因在肿瘤中的表达及作用
- Author:
Hong WANG
;
Xiuhong JIA
- Publication Type:Journal Article
- Keywords:
Neoplasms;
HA1 1 7 gene
- From:
Journal of International Oncology
2015;(10):747-749
- CountryChina
- Language:Chinese
-
Abstract:
HA1 1 7,as a multiple drug resistance(MDR)gene,has recently been discovered.It may mediate the MDR of tumor through Bcl-2 anti-apoptotic pathways.HA1 1 7 gene exists high expression in leuke-mia,lymphoma,breast cancer,neuroblastoma,colon adenocarcinoma and so on,and its overexpression is closely associated with the MDR and poor prognosis of these tumors.
