Study progress of microRNAs in lung development and pulmonary diseases
10.3760/cma.j.issn.2095-428X.2015.22.020
- VernacularTitle:微小RNA与肺发育及肺相关疾病的研究进展
- Author:
Yun LIU
;
Xiaoyu ZHOU
- Publication Type:Journal Article
- Keywords:
Lung development;
Pulmonary disease;
microRNA
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(22):1748-1750
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a class of small endogenous RNAs, which handle post-transcriptional gene regulation activity through targeting messenger RNAs.As the deep understanding of them, miRNAs had been found to participate in numerous basic biological processes, including the normal growth process of tissues and organs ,as well as the pathologic course of diseases.Different miRNAs may be involved in different tissues and organs, the same miRNA may have different expression in various physiological process or stages of pathological conditions.Now, the recent studies about the miRNAs in the lung development and pulmonary diseases were reviewed.