Optimization of Ethanol Extraction Technology forXiao-Xu-MingDecoction by Orthogonal Design with Multi-target
10.11842/wst.2015.09.008
- VernacularTitle:多指标正交试验法优选小续命汤醇提组药材的乙醇提取工艺＊
- Author:
Renjie WANG
;
Enli ZHOU
;
Miao LI
;
Jianping QIN
;
Yun WU
;
Yongcheng SUN
;
Guanhua DU
;
Wei XIAO
- Publication Type:Journal Article
- Keywords:
Multi-target components;
Xiao-Xu-Mingdecoction;
paeoniflorin;
ferulic acid;
tetrandrine;
comprehensive evaluation;
entropy method
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;(9):1795-1800
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to optimize the ethanol extraction technology ofXiao-Xu-Ming (XXM) decoction. The extraction rates of paeoniflorin, ferulic acid, tetrandrine and yield extract were used as comprehensive evaluation indexes. The amount of ethanol, extraction times, extraction time and concentration of ethanol were selected as factors. The orthogonal design was used to optimize ethanol reflux extraction technology of XXM decoction. The results showed that the optimum extraction conditions were as follows: refluxing extracted 3 times with 10 folds, 70% ethanol, 1.5 h for each time. It was concluded that the optimized extraction process was objective, practical, reasonable and stable, which provided experimental basis for industrial production of XXM decoction.
