Effects of Yunnan Baiyao on the hemolytic phenomena and plasma clotting ability of Staphylococcus aureus
10.3969/j.issn.1673-4130.2015.17.009
- VernacularTitle:云南白药对金黄色葡萄球菌溶血现象和血浆凝固能力的影响
- Author:
Shaolong HUANG
;
Jieming WANG
;
Weidong YANG
;
Junbing JIANG
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
traditional Chinese medicine;
hemolysin;
plasma coagulase
- From:
International Journal of Laboratory Medicine
2015;(17):2476-2477
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Study the effect of Yunnan Baiyao on the hemolysis and plasma coagulation ability of Staphylococcus aureus.ToseeknewmechanismofYunnanBaiyao′sapplicationonthebasisofanti‐virulence.Methods 0.5MCFbacterialiquidof Staphylococcus aureus standard strains(ATCC29213) were prepared and cultured in blood agar plates which containing Yunnan Baiyao of different concentrations at 37 ℃ for 24 h .Then the diameter of hemolysis rings were measured and recorded .0 .1 MCF bacteria liquids treated with Yunan Baiyao of different concentrations were prepared ,and 20μL of the bacteria liquid were added in‐to 80 μL plasma ,then cultivated at 37 ℃ for 24 h to observe the phenomenon of solidification .Results There was significant differ‐ence among the effects of Yunan Baiyao of different concentrations on the Staphylococcus aureus hemolytic rings(P<0 .05) ,and the drug concentrations inversely proportional to the diameter of hemolysis .Plasma coagulation effect of bacteria was not obvious differ‐ent after the treatment with different concentrations of Yunnan Baiyao ,and not had any regular pattern(P>0 .05) .Conclusion Yunnan baiyao can inhibit the growth of Staphylococcus aureus and its hemolytic ability but has no significant effect on plasma clot‐ting enzyme .
