Research progress in diagnosis of early-onset neonatal sepsis
10.3969/j.issn.1000-3606.2015.09.016
- VernacularTitle:新生儿早发型败血症诊断进展
- Author:
Jiangyi LU
;
Luquan LI
- Publication Type:Journal Article
- Keywords:
neonate;
early-onset neonatal sepsis;
advance of diagnosis
- From:
Journal of Clinical Pediatrics
2015;(9):822-826
- CountryChina
- Language:Chinese
-
Abstract:
Early-onset neonatal sepsis (EONS) is one of the major causes of mortality in neonates, especially in very low birth weight infants. EONS has no speciifc manifestations, and progresses rapidly and unexpectedly. EONS is often missed diag-nosed or even misdiagnosed due to the absence of ideal diagnostic methods in current clinical practice, and this dilemma leads to the high mortality of EONS. Therefore the accurate diagnosis in the early stage of EONS is very important. This review describes the progress in diagnostic methods of EONS including culture, blood cell counts, molecular biological technique, procalcitonin and C-reactive protein measurements, cytokine proifling and some other novel means. It may provide useful information for early diagnosis of EONS.