Mitochondrial cardiomyopathy
10.3969/j.issn.1000-3606.2015.09.017
- VernacularTitle:线粒体心肌病
- Author:
Huiyun PENG
;
Shuangjie LI
- Publication Type:Journal Article
- Keywords:
mitochondria;
cardiomyopathy;
aerobic metabolism;
mitochondrial DNA mutations
- From:
Journal of Clinical Pediatrics
2015;(9):827-830
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondria are the energy factory of all the cells, the center of aerobic metabolism, and essential for the me-tabolism of cells. Mitochondrial cardiomyopathy refers to myocardial damage caused by mitochondrial dysfunction and is char-acterized by cardiac structural and (or) functional abnormalities. The typical clinical feature of mitochondrial cardiomyopathy is hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmias, noncompaction of left ventricular and heart failure. This article focuses on the pathophysiology, clinical manifestations and possible treatments of mitochondrial cardiomyopathy.
