The progress in defensin research
10.3969/j.issn.1000-3606.2015.09.018
- VernacularTitle:防御素研究进展
- Author:
Qingfeng HU
;
Tongxin CHEN
- Publication Type:Journal Article
- Keywords:
defensin;
antimicrobial peptides;
breast milk
- From:
Journal of Clinical Pediatrics
2015;(9):831-834
- CountryChina
- Language:Chinese
-
Abstract:
Defensin is a cysteine-rich, low molecular weight and cationic antimicrobial peptide. Human breast milk con-tains high level of defensin. The defensin in human breast milk can not only inhibit the growth of various pathogenic microorgan-isms, but also promote the development of infant immune system and reduce the incidence of infantile upper respiratory infection. Nowadays, the roles of defensin in breast milk is more recognized. This paper focuses on the molecular characteristics of human defensin, its antibacterial and antiviral roles, and the latest progress in defensin research.