Effect of combination of atorvastatin and dual antiplatelet therapy on serum CRP, cerebral vascular event recurrence rate and carotid artery plaque in cerebral infarction patients
- VernacularTitle:瑞舒伐他汀与双抗血小板联合治疗对脑梗死患者血清CRP、脑血管事件复发率及颈动脉斑块影响研究
- Author:
Guangjun DUAN
;
Zhou WAN
;
Ziyang JIANG
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
cerebral infarction;
dual antiplatelet;
recurrent cerebral vascular events
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):99-101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effect of combination of rosuvastatin and dual antiplatelet therapy on the serum CRP, cerebral vascular event recurrence rate and carotid artery plaque in cerebral infarction patients.Method 60 cerebral infarction patients were seleted and divided into the control group and the experiment group by different treatment(n=30).Two groups were treated by corresponding drugs.The serum levels of IMT, CRP, plaque area, plaque number and the cases of recurrent cerebral vascular events after 6 month were compared after treatment a month.Results Compared with the control group after treatment,the serum CRP were lower(P<0.05),the recurrence rate of cerebral vascular events were lower(P<0.05),the IMT value, patch area and the number of carotid plaques were lower(P<0.05).Conclusion Rosuvastatin and dual antiplatelet combination therapy has good clinical effect for cerebral infarction patients,and have the clinical guiding significance.
