Effect of compound amino acid 15-peptide 2 injection on levels of tumor markers in serum of postoperative patients with liver cancer surgery
- VernacularTitle:复方氨基酸15双肽2注射液对肝癌术后患者血清肿瘤标志物水平影响研究
- Author:
Hua JIANG
;
Dongbin LIU
;
Kuo LIANG
;
Jiafeng LIU
- Publication Type:Journal Article
- Keywords:
compound amino acid 15-peptide 2 injection;
liver cancer;
tumor markers;
negative nitrogen balance;
immune function
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):48-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analysis effect of compound amino acid 15 peptide 2 on levels of tumor markers in serum of postoperative patients with liver cancer.Methods 42 postoperative patients who were diagnosed with liver cancer were collected.All patients were randomly divided into experimental group and control group, 21 cases in each group.The two groups of patients were given the corresponding parenteral nutrition therapy, after treatment, the serum tumor markers, T lymphocytes, liver function and nitrogen balance related indicators in all patients were detected.Results After treatment, compared with control group, the serum alpha fetal protein(AFP),carbohydrate antigen 19-9(CA19-9) and carcino embryonie antigen(CEA) levels were lower in the experimental group (P<0.05); the serum CD3 +T cells, CD4 +T cells and CD4 +/CD8 + ratio levels were lower in the experimental group (P<0.05); the serum alanine amino transferase (ALT), aspartate aminotransferase (AST) and total bilirubin(TBIL) levels were lower in the experimental group (P<0.05); the patients in the experimental group changed to positive nitrogen balance(P<0.05).Conclusion The diluted compound amino acid 15-2 injection for intravenous injection,can significantly reduce the level of serum tumor markers in patients with liver cancer, improve the immune function of patients, correct negative nitrogen balance, protect liver function.
