Effect of ShenQi FuZheng injection on serum CA19-9,CRP and CD4+lymphocyte subsets in patients after laparoscopic radical resection of colon cancer
- VernacularTitle:参芪扶正注射液对腹腔镜结肠癌根治术患者术后血清CA19-9、CRP、CD4+淋巴细胞亚群影响研究
- Author:
Ke MIAO
;
Anan GONG
- Publication Type:Journal Article
- Keywords:
ShenQi FuZheng injection;
laparoscopic radical resection of colon cancer;
carbohydrate antigen 19-9;
C-reaction protein;
CD4 +lymphocyte subsets
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):51-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse effect of ShenQi FuZheng injection on serum carbohydrate antigen 19-9(CA19-9), C-reaction protein(CRP) and CD4 +lymphocyte subsets in patients after laparoscopic radical resection of colon cancer.Methods 58 patients after laparoscopic radical resection of colon cancer were collected.All patients were randomly divided into experimental group and control group according to the different drugs, 29 cases in each group.Patients were given the corresponding drug treatment after operation, after the treatment, the serum levels of CA19-9, CRP and venous blood T lymphocyte level were detected in all patients.Results Compared with before treatment, CA19-9 and CRP level in serum were lower (P<0.05) , CD4 +cells, CD4 +/CD8 +, and NK cells were higher(P<0.05);Compared with control group after treatment, the serum CA19-9 and CRP level were lower in the experimental group (P<0.05); the levels of venousblood CD4 +cells, CD4 +/CD8 +and NK cells were higher in the experimental group (P<0.05).Conclusion ShenQi FuZheng injection can significantly reduce the serum CRP and CA19-9 levels in patients after laparoscopic radical resection of colon cancer, improve the levels of venous blood CD4 +cells, CD4 +/CD8 +and NK cells, improve immune function, and have a guiding significance for clinica.
