Effect of positive liver soup on serum LEP, ADP levels and insulin resistance in patients with hepatitis B cirrhosis
- VernacularTitle:正肝汤对乙肝肝硬化患者血清LEP、ADP水平以及胰岛素抵抗的影响
- Author:
Jieru WU
;
Limiao LIN
- Publication Type:Journal Article
- Keywords:
hepatitis B cirrhosis;
positive liver soup;
leptin;
adiponectin;
insulin resistance
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):65-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study effect of positive liver soup on serum leptin (LEP), adiponectin (ADP) and insulin resistance (IR) in patients with hepatitis B cirrhosis.Methods 68 cases of hepatitis B patients with cirrhosis according to randomized divided into the control group (34 cases) and treatment group (34 cases).Oral treatment administered to the control group (Inosine Tablets and vitamin C),treatment group in the control group based on liver soup treatment, treatment for 3 months, serum leptin (LEP),adiponectin (ADP) and insulin resistance (IR) index before and after treatment were detected.Results Before treatment, there was no significant difference between ADP and LEP in the control group and the treatment group.After 3 months of treatment, there was no significant difference between ADP and LEP level in control group, while the level of ADP and LEP in treatment group were significantly decreased (P<0.05), and were significantly lower than that in control group (P<0.05).There was no significant difference in FPG, fasting insulin level and IRS index between the control group and the treatment group before treatment.After 3 months of treatment, the control group FPG, fasting insulin level and IRS index were not significantly different.FPG, fasting insulin and IRS index in the treatment group were significantly decreased (P<0.05), and were significantly lower than those in the control group (P<0.05).Conclusion Positive liver soup can reduce serum LEP, ADP level, and improve IR in treatment of hepatitis B liver cirrhosis.
